Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.
方法以拉霉素为起始原料,经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基酸酯化和环等反应标化物。
Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.
方法以拉霉素为起始原料,经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基酸酯化和环等反应标化物。
The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.
组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。
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