3.Besides central DI further underlying etiologies of DI can be due to other primary forms (renal origin) or secondary forms of polyuria (resulting from primary polydipsia).
4.Stones is for calcium-based kidney stones or gallstones that can form, thrones refers to the toilet to remind you of the polyuria or frequent urination that results from impaired sodium and water reabsorption.
5.As beta cells are lost and insulin levels decrease, glucose levels in the blood start to increase, and patients develop hyperglycemia, which leads to similar clinical signs that I mentioned before, like polyphagia, glycosuria, polyuria, and polydipsia.