cyano 4’ methyl phenylbenzene, a key intermediate of Sartan drug, was synthesized from 4 bromotoluene and 2 bromobenzonitrile in the present of cuprous bromide as a catalyst. The yield is 50%.
溴化亚铜为催化剂,将邻苯甲腈与对溴甲苯偶联制
成沙坦类药物的关键中
体2氰基4′甲基联苯,收率50%。
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bromotoluene
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n. 溴甲苯
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bromosalicylaldehyde, bromoseltzer, bromostyrene, bromosulfophthalein, bromothymol blue, bromotoluene, bromotolunitrile, bromotrifluoromethane, bromouracil, bromoxynil,
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