N-phosphoryl amino acids could be catalyzed by imidazole to result in solvolysis such as ester exchanges on phosphorus, esterification, formation of peptides and N→O migration of the phosphoryl group.
咪
酰化氨基酸的活化反应具有较强的催化作用，酰化丝、苏氨酸在咪催化
不仅能发生溶剂解反应，如上酯交换、羧基活化成酯、成肽及酰基的N→O迁移
，
还会发生分子内环化反应；
