In the novel The Stranger by absurdist philosopher Albert Camus, the main character Meursault finds himself, in a way, apart from the world around him.
He's not following conventions, doesn't really mingle with his environment, and has a unique way of responding to events.
For example, when his mother dies, his indifference leads those around him to perceive him as heartless, even possibly a psychopath.
And after shooting and killing a thug who attacks him, he displays no remorse.
But later on in the story, we learn that Meursault isn't a person with bad intentions who purposefully does evil deeds.
He's just different, the odd one out, as he's detached from accepted conduct.
Although often different from Meursault, many experience estrangement from the world. These people have drifted away from others. They became disentangled.
This estrangement could have a particular cause, such as a bad experience with people.
Or maybe, like Meursault, one's personality doesn't quite jive with the rest, making one socially incompatible to a certain extent.
Whatever the reason, this (often) self-imposed seclusion isn't always without dangers.