94 patients meeting criteria for insomnia were randomly assigned into zopiclone group and alprazolam group,treated for 4 weeks.

对94例患者,随机分为佐匹克隆和阿普唑仑。疗程4周。

A reversed phase high performance liquid chromatographic method (external standard method) was developed for the determination of zopiclone in serum.

建立了测定血清中佐匹克隆的效液色谱法(外标法)。