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Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙基结构的三醇类化合物的抗活性。

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OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪类、三类、烯丙胺类、抗生素类等全身用抗的研发进展市场应用趋

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Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

醇属三类杀剂,可抑制中麦角甾醇的生物合成,主要商品有:立克莠、富力库、立克三种。

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By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1,3,4-三为原料,在稀碱存在下与二卤代烷反应合成了10个新的标题化合物。

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Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究了1,2,4三酮3(TO)衍生物的合成,结果表明TO在多种硝化条件下均可制得3硝基1,2,4三酮5(NTO),同时还合成了TO的二取代硝基苯衍生物。

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3G, 401(K), a,

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