Nicotine directly increases dopamine levels in the nucleus accumbens, but it also increases glutamate levels which gets the ventral tegmentum neurons to release more dopamine onto the nucleus accumbens.

尼古丁可以直接提高核的多巴胺水平，但同时也提高谷氨酸盐水平，使侧被盖区神经元释放更多的多巴胺核。

For example, increased dopamine in the mesolimbic system, a reward pathway composed of the ventral tegmentum and the nucleus accumbens causes pleasure, improved attention and mental processing, and working memory.

例如，人体的一个由侧被盖区和核组成的奖赏路脑边缘系统里多巴胺的增多，可以引起欣快感、注意力提高、思维变敏捷、记忆力增强等效应。

For example, increased concentrations of dopamine in the brain's reward pathway, which includes the nucleus accumbens, ventral tegmentum, and prefrontal cortex, produce intense feelings of euphoria, pleasure, and the emotional " high" associated with cocaine.

例如，包括核、侧被盖和前额叶皮层在内的大脑奖赏途径多巴胺浓度的增加，在可卡因的帮助下，能够产生强烈的兴奋、快感，以及很“嗨”的感觉。

Nicotine also decreasing the activity of inhibitory GABA neurons in the ventral tegmentum, so by inhibiting the inhibitory neurons there's a double negative, which means that this is one more way to create an increase in dopamine levels.

尼古丁还能减少侧被盖区抑制性GABA神经元的活动，抑制抑制性神经元会起到负负得正的作用，从另一方面提高了多巴胺水平。