It receives dopaminergic innervations from ventral tegment area and SNc, and noradrenergic and serotonergic innervations from the locus ceruleus (LC) and dorsal raphe nucleus (DRN), respectively.

腹内侧前额叶皮层主要接受来自腹侧被盖（ventral tegmental area，VTA）SNcDA经纤维投射，以及来自蓝斑去甲肾上腺素（noradrenaline，NA）中缝背核5-HT经纤维投射。