Hyperplasia of synovium leads to formation of pannus which destroys cartilage and bone in the affected joint.
大量增膜组织会导致血管成,进而逐渐侵软,造成关节损伤。
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As " type A" cells in the synovium attempt to remove the debris, immune cells like lymphocytes and macrophages are recruited into the synovial membrane, which produces proinflammatory cytokines that ultimately cause inflammation of the synovium as well, called synovitis.
滑膜上的A型细胞努力清除这些碎片的同时,免疫细胞(细胞、巨噬细胞)也被募集进入滑膜,产生炎症因子,最终导致滑膜炎。
The synovium's composed of loose connective tissue, blood vessels, lymphatic vessels, and on the surface—" Type A" cells that clear cellular debris and " Type B" cells that produce components of synovial fluid, which helps lubricate the two articular surfaces.
滑膜由松散结缔组织、血管、管组成;在滑膜表面,A型细胞清理细胞碎屑,B型细胞产生滑液成分,滑液能够润滑两块的表面。