Hyperplasia of synovium leads to formation of pannus which destroys cartilage and bone in the affected joint.
大量增生的滑膜导致血管的生成,进侵蚀软骨,造成关节的损伤。
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As " type A" cells in the synovium attempt to remove the debris, immune cells like lymphocytes and macrophages are recruited into the synovial membrane, which produces proinflammatory cytokines that ultimately cause inflammation of the synovium as well, called synovitis.
膜上的A型胞努力清除这些碎片的同时,胞(如淋巴胞、巨噬胞)也被募集进入膜,产生炎症因子,最终导致膜炎。
The synovium's composed of loose connective tissue, blood vessels, lymphatic vessels, and on the surface—" Type A" cells that clear cellular debris and " Type B" cells that produce components of synovial fluid, which helps lubricate the two articular surfaces.
膜由松散结缔组织、血管、淋巴管组成;在膜表面,A型胞清理胞碎屑,B型胞产生液成分,液能够润两块关节的表面。