For example, rickets or osteomalacia can occur in chronic liver disease, due to the liver's inability to turn inactive vitamin D into 25-hydroxy-vitamin D.
Without this vitamin variety, humans face deficiencies that cause a range of problems, like fatigue, nerve damage, heart disorders, or diseases like rickets and scurvy.
With both rickets and osteomalacia, symptoms include diffuse bone and joint pain, proximal muscle weakness, bone fragility, and increased risk of fractures with minimal trauma.
He focused on breathing techniques to assist with his asthma, and by exercising outside in his shorts, was able to cure his rickets which is caused by a vitamin D deficiency.
For osteomalacia and rickets, the key symptoms are diffuse bone and joint pain, proximal muscle weakness, bone fragility, and increased risk of fractures with minimal trauma.
Charles developed his ability to talk later than most children, while he was a sickly infant, one who probably suffered from rickets which weakened his ankles in his youth.
Let's hear about how rickets – a disease caused by a lack of Vitamin D in the diet – is affecting some children in the UK. This is BBC reporter Mike Williams.
Treatment for both rickets and osteomalacia typically involves oral vitamin D supplementation and treating the underlying cause which could be any condition affecting the organs responsible for vitamin D activation.