The team found that the allergic reactions caused cells to produce more prostaglandins, a type of hormone.

该小组发现过敏反应导致细胞更多的列腺素，这是一种激素。

A few years later, other scientists came across prostaglandins again.

几年后，其他科学家又发现了列腺素。

That ring of sclerotic tissue often produces prostaglandins, which are small molecules that trigger the sensation of pain.

硬化的骨组织通常列腺素，这些小分子引发疼痛感。

In 1976, researchers discovered cyclooxygenase, or the COX enzyme, which makes a few different biomarkers, including prostaglandins.

1976 年，研究人员发现了环氧合酶，即 COX 酶，它了几种不同的物标志物，列腺素。

More COX binding, less prostaglandin, so less pain.

更多的 COX 结合，更少的列腺素，所以带的是更少的疼痛。

When it receives this message, the hypothalamus produces another molecule called prostaglandin E2, which gears it up for war.

当下丘脑接受到这种信息，它另一种分子叫做列腺素E2，在战争中发挥了重要的作用。

Soon after birth, the foramen ovale closes and prostaglandin E2 levels fall, causing the ductus arteriosus to close off.

出后不久，卵圆孔闭合、列腺素E2水平下降，导致动脉导管闭合。

And what they do is they block the release of prostaglandins.

他们所做的是阻止列腺素的释放。

That reduces the production of prostaglandins, hormone-like compounds that normally cause inflammation and pain.

这减少列腺素的，列腺素是通常引起炎症和疼痛的类激素化合物。

They were able to tie prostaglandins to fever, inflammation, and headaches, so this went a long way toward explaining how aspirin worked.

他们能够将列腺素与发烧、炎症和头痛联系起，所以这对解释阿司匹林的作用有很大帮助。

Aspirin and ibuprofen block production of one class of these tuning chemicals, called prostaglandins.

阿司匹林和布洛芬可阻止一种调节化学物质的，称为“列腺素”。

It acts in the brain, it inhibits the pain and inflammation producing chemicals called prostaglandins.

它作用于大脑，抑制疼痛和炎症，称为列腺素的化学物质。

In response, it produces bicarbonate, mucus, and phospholipids called prostaglandins to maintain the integrity of its own lining.

作为回应，它碳酸氢盐、粘液和称为列腺素的磷脂，以维持自身内膜的完整性。

While COX-2 produces prostaglandins during inflammation, a COX-1 enzyme has the added duty of making prostaglandins to protect the lining of your stomach.

虽然 COX-2 在炎症期间列腺素，但 COX-1 酶还有制造列腺素保护胃内膜的额外职责。

When we menstruate, the lining of the uterus releases substances that are made into chemicals called prostaglandins and other inflammatory mediators.

当我们月经时，子宫内膜释放出一种物质， 这些物质被制成称为列腺素和其他炎症介质的化学物质。

They showed that the drug interrupts the production of certain chemicals called prostaglandins, which control the transmission of pain sensations and inflammation.

他们表明，这种药物中断某些称为列腺素的化学物质的，这种化学物质控制痛觉和炎症的传递。

For example, IL-4 leads the production of IgE antibodies which coat mast cells and stimulate them to release granules containing things like histamines, leukotrienes and prostaglandins.

例如，IL-4导致了IgE抗体的，覆盖在肥大细胞表面，并刺激它们释放含有像组胺、白三烯和列腺素等物质的颗粒。

That's because cytokines and prostaglandin can reach even higher structures in your brain, disrupting the activity of neurotransmitters, like glutamate, endorphins, serotonin, and dopamine.

这是因为细胞因子和列腺素可以到达你大脑中更高的结构，破坏神经递质活性，如谷氨酸，内啡肽，血清素，和多巴胺。

Well, the drug indomethacin can be used to close a PDA because it's a type of non-steroidal anti-inflammatory drug, or NSAID, and it inhibits prostaglandin E2.

而药物吲哚美辛被用使PDA闭合，因为它是种非甾体抗炎药，或称NSAID，可抑制列腺素E2。

Cortisol also helps to dampen the inflammatory and immune response by reducing the production and release of inflammatory mediators, like prostaglandins and interleukins, as well as inhibiting the proliferation of T-lymphocytes.

皮质醇也有助于抑制炎症和免疫反应，降低如列腺素和白细胞介素等炎症介质的制造和释放，也抑制T淋巴细胞的增殖。