With most cases, the macrophage then fuses the phagosome with a lysosome which has hydrolytic enzymes that can pretty much break down any biochemical molecules.
Once it reaches the lungs, it gets ingested by alveolar macrophages and inside macrophages, it gets wrapped up in a vesicle called phagosome, which normally merges with lysosomes to kill invading bacteria.
Neutrophils use a process called phagocytosis - that's where they get near a pathogen and reach around it with their cytoplasm to " swallow" it whole, so that it ends up in a phagosome.