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Most cases of hyponatremia are associated with low serum osmolality (so-called hypo-osmolar hyponatremia).

大多数低钠渗透压降低(所谓低渗性低钠症)。

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Osmosis-内分

Type A is completely erratic and is independent of the plasma osmolality.

A型为ADH释放紊乱,且独立渗透压变化。

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Osmosis-解剖与生理

They also regulate blood pH, volume, pressure, osmolality as well as produce hormones.

它们也调控液pH值、容量、压、渗透压,并产生多种激素。

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Osmosis-内分

Type D is the least common type of SIADH where ADH secretion is completely normal, yet urine osmolality is still high.

D型是最少见的类型,其中ADH的分全正常,但尿液的渗透压仍较高。

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Osmosis-内分

ADH levels tend to be very high so the maximum amount of fluid is retained, causing urine osmolality to be very high.

ADH水平会变得非常高,导致大量水分在体内潴留,引起尿液的渗透压大幅升高。

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Osmosis-内分

Low blood sodium levels and low plasma osmolarity combined with high urine osmolality and high urine sodium is a giant red flag for SIADH.

症和渗透压合并高尿液渗透压、高尿,是SIADH的警示。

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Osmosis-内分

When I drink a glass of water and that water is absorbed into my blood, my plasma osmolality drops, which means I'm diluting my blood with the water.

当我们饮用一杯水后,水分吸收至液中,渗透压降,意味着液被稀释。

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Osmosis-内分

The part of my brain called the hypothalamus sees this drop in plasma osmolality and tells the pituitary gland to slow down the release of ADH (that's enough! ) .

当下丘脑感知到渗透压的下降,就会让垂体减缓ADH的释放:“够了够了!”

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Osmosis-内分

Now suppose ADH continues to be released even though my plasma osmolality has dropped, we're going to continue retaining water, and as we drink more and more water, we might expect our plasma osmolality to continue dropping.

现在假设即便渗透压已经下降,ADH仍在继续被释放入,水分就一直保留在管内,再加上我们继续饮水,可以预想到渗透压继续降

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