1.Moreover, increased breakdown of arachidonic acid results in increased production of proinflammatory lipid mediators like prosta glandines, thromboxanes and leukotrienes.
2.Individuals with more severe forms of asthma might need additional treatments like daily corticosteroids, long-acting beta-adrenoceptor agonists, or leukotriene antagonists.
3.For example, IL-4 leads the production of IgE antibodies which coat mast cells and stimulate them to release granules containing things like histamines, leukotrienes and prostaglandins.