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1.Antiestrogen. Selective protein kinase C (PKC) inhibitor. Induces apoptosis.

1.抗雌激性PKC抑制剂。诱导凋亡。

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2.Displays cytostatic and cytotoxic activity. Inhibitor of EGFR kinase. Shows antiangiogenic activity.

2.显示细胞生长抑制和细胞毒活性。EGFR激酶抑制剂。有抗血管生成活性。

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3.Altenusin was reported as myosin light chain kinase inhibitor and sphingomyelinase inhibitor.TAN-420E has antitumor activity.

3.TAN-420E曾报有抗肿瘤活性,易氧化为Herbimycin A,后者是很好的除草剂,并具有一定抗菌活性。

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4.Novel oncogene with kinase-domain (NOK) can activate multiple mitogenic signaling pathways including the janus kinases (JAK) and signal transducer and activator of transcription proteins (STAT).

4.摘要NOK能激活包含JAK-STAT信号内的多种促细胞有丝分裂信号路。

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5.Uridine-cytidine kinase (UCK) (EC 2.7.1.48) is a pyrimidine ribonucleoside kinase that catalyzes the phosphorylation of uridine and cytidine to UMP and CMP.

5.本论文的第一章中主要是对人类尿苷胞苷激酶(UCK,EC 2.7.1.48)基因进行的一系列研究。

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Osmosis-肌骨

1.Muscle proteins like creatine kinase and myoglobin start leaking out into the bloodstream.

肌肉中蛋白质,如肌酸激酶与肌红蛋白,会漏入血液中。

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健身知识科普

2.Time to exhaustion, ratings of perceived exertion, heart rate, and fatigue factors, such as serum lactate and creatine kinase levels.

运动至力竭时,感知体力,心率,疲劳因素,如血清乳酸和肌酸激酶水平。

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名人73个快问快答

3.Did you know that molecular dynamics can be used to study proteins, enzymes and kinases?

您知道动力学可用于研究蛋白质、酶和激酶吗?机翻

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经济学人-科技

4.Xalkori blocks the growth of tumours caused by a mutant form of the gene which encodes a signalling molecule known as anaplastic lymphoma kinase.

Xalkori能够抑制由编码信号变性淋巴瘤激酶基因突变体所导致癌细胞增长。

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Osmosis-遗传

5.The most common type is Non-Homologous End Joining where a protein complex called DNA protein kinase begins by binding to each end of the broken DNA.

最常见类型是非同源末端连接:一个叫做DNA蛋白激酶蛋白质复体首先会断裂DNA末端。

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豪斯医生

6.Blood tests show elevated creatine kinase, what does that tell you?

血液测试显示肌酸激酶升高, 这告诉你什么?机翻

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Osmosis-肌骨

7.When Rhabdomyolysis develops, the laboratory workup can show elevated levels of creatine kinase and myoglobin, while urinalysis can show tea-colored urine due to high levels of myoglobin.

发生横纹肌溶解时,实验室检查可发现肌酸激酶和肌红蛋白水平升高,尿检可见由肌红蛋白升高导致茶色尿。

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医学之光:人类与疾病斗争

8.Laboratory results on hospital days 3 and 5 (illness days 7 and 9) reflected leukopenia, mild thrombocytopenia, and elevated levels of creatine kinase (Table 1).

住院第 3 天和第 5 天(发病第 7 天和第 9 天)实验室果反映出白细胞减少、轻度血小板减少和肌酸激酶水平升高(表 1)。机翻

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Osmosis-肌骨

9.Over time, cellular proteins like creatine kinase, or CK, start escaping the damaged cell and calcium starts to enter the cell, and this ultimately leads to cell death.

一长,如肌酸激酶(CK)等细胞蛋白开始从受损细胞中逸出,而钙离开始进入细胞,这最终造成细胞死亡。

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健身知识科普

10.Same goes for indirect muscle recovery markers, like creatine kinase and muscle voluntary isometric force contraction, where active cooldowns don't seem to change much of these recovery factors.

果同样在测量接肌肉恢复标志物中成立,例如,肌酸激酶活性和肌肉自发等长收缩力,主动冷身不会对这些恢复因素造成影响。

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Fast Facts Non-Small-Cell Lung Cancer

11.Mechanisms of AR to MET-TKIs include MET kinase domain mutations and high levels of amplification of the MET exon 14-mutant allele in up to 35% of cases.

AR 至 MET-TKI 机制包括 MET 激酶构域突变和高达 35% 病例中 MET 外显 14 突变等位基因高水平扩增。机翻

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Scishow 精选系列

12.See, phorbols mimic the action of diacylglycerol — a fatty molecule your body uses in a number of ways, including to activate an enzyme called protein kinase C, or PKC for short.

因为佛波醇类模拟了二酰基甘油活动,二酰基甘油这种脂肪在你身体里有很多作用,它能激活一种蛋白激酶C,简称PKC。

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跟着小姐姐看科技

13.At this point in the episode I was expecting to be talking about cancer vaccines or kinase  inhibitors or immunotherapy - something that I keep hearing about in the news.

在这一集这一点上,我本以为会谈论癌症疫苗或激酶抑制剂或免疫疗法——我不断在新闻中听这些内容。机翻

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Fast Facts Non-Small-Cell Lung Cancer

14.ROS1 rearrangement ROS1 rearrangements lead to fusions of the ROS1 tyrosine kinase domain (on chromosome 6) with partner genes, usually on other chromosomes, and occur in approximately 2% of NSCLCs.

ROS1 重排 ROS1 重排导致 ROS1 酪氨酸激酶构域(位于 6 号染色体上)与伴侣基因(通常位于其他染色体上)融,发生在大约 2% NSCLC 中。机翻

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