It is synthesized by oxidation of isocitrate, coupled to the reduction of NAD.

由异柠氧化而，伴有NAD的还原。

Moreover, the activities of isocitrate lyase and isocitrate dehydrogenase in the 0 P-treated cells were 1.48 and 0.75 times higher than in the control at day 8 of the treatment.

在第8 d，缺条件下的细胞异柠解酶活性和异柠脱氢酶活性分别是对照的1.48倍和75%。