Four is absolutely excruciating the debilitating, incapacitating, just shut you down, just absolute sheer pain.

四级是绝对折磨人，使人衰弱，丧失能力，让你晕厥，纯粹痛苦。

It can be debilitating, and cleaning won't solve the problem.

它是很累人，并没有办法解问题根源。

Shame can be crippling and debilitating.

羞愧会起到削弱作用。

For others, the effects may include debilitating cramps, bloating, migraines and depression.

对其他人来说，其影响可能包括使人虚弱抽筋、腹胀、偏头痛和抑郁。

But the noise of it has grown deafening and debilitating in the past two years.

但是在过去两年里，恐惧之声变得震耳欲聋，令人衰弱。

Another study of Korean immigrants found the discrimination was linked to debilitating mental health effects.

另一个针对韩国移民研究发现，歧视和削弱心理健康影响有关。

Though temporary, opioid withdrawal can be incredibly debilitating.

阿片类药物断症状虽然短暂， 却能让人极度衰弱。

And yet the U.S. market has offered no drug expressly designed to prevent these debilitating headaches.

尽管如此，美国市场还是没有专门用来预防这些令人难以承受头痛药物。

But he insisted Mr. Trump's behavior is more embarrassing for the country than debilitating to his efforts.

但他坚称，与妨碍疫苗工作相比，特朗普行为更是令美国难堪。

With yet more billions of years looming ahead they will be struck down with a debilitating ennui.

未来还有数十亿年要面对，这些永生者将会感到一种压倒一切无聊感。

The ruling centred on two women with debilitating conditions, both of whom died before it was handed down.

关注了两名身体衰弱妇女，两人都在宣告之前死亡。

On other occasions, though, autism manifests as part of a range of cognitive problems. Then, the condition is debilitating.

然而，另一些场合，自闭症表现为一系列认知问题一部分。

So even though we might live longer, we do tend to suffer more for some of these debilitating conditions.

所以即使我们可能活得更长，但我们确实倾向于在这些使人衰弱情况下遭受更多痛苦。

Well, she does say that too much shame can be crippling and debilitating.

好吧，她确实说太多羞愧会起到削弱作用。

And that is these debilitating medical ailments. They have become known as the Havana Syndrome.

就是那些使人衰弱医学疾病，众所周知“哈瓦那综合症”。

He was the best-known theoretical physicist of his time despite being afflicted with ALS which left him debilitated for decades.

尽管几十年来受肌萎缩侧索硬化（ALS）折磨，身体十分虚弱，他仍曾是当下最著名理论物理学家。

I hear every day from Americans whose loved ones are suffering from addiction and other debilitating diseases.

我每天都从人们那里听到这些, 他们爱着人们在忍受着药物上瘾, 其他人忍受着使人衰弱疾病。

Consumers started calling out some very debilitating problems with the conventional construction of the American potato chip.

消费者开始指出美国薯片传统结构存在一些非常严重问题。

During heart attacks and other medical emergencies, people often die or sustain debilitating organ damage from oxygen deprivation.

在心脏病突发以及其他紧急医疗情况时，人们经常因为缺氧而死亡或是器官受损。

He urged MPs to come together to end what he described as this debilitating feud and vote for his deal today.

他敦促议员们团结起来，结束这场折磨人长期争执，并在今天投票支持他协议。