Mismatches between myocardial fatty acid uptake and utilization lead to the accumulation of cardiotoxic lipid species,and cause lipotoxic cardiomyopathy.
心游离肪酸的摄入和利用的失协调导致心质积聚并进而起毒性心。
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Later symptoms include needing a wheelchair because of severe weakness, developing respiratory failure because of a weak diaphragm, scoliosis, and developing dilated cardiomyopathy and arrhythmias since the dystrophin protein is also expressed in heart muscle.
后期症状包括,由于严重无力需坐轮椅,由于膈无力会发生呼吸衰竭、脊柱侧凸,因为抗萎缩蛋白也表达于纤维,还会引发扩张型和律失常。