CONCLUSION The QSAR model can predict the MIC of carbapenems and select the biologic-activity compounds, which offer a new way of thinking and references of carbapenems compounds design.
结论所建立的QSAR模型能有
进行碳青霉烯类化
的MIC值的预测和化
选，为这类新药开发提供新的参考和思路。
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3G, 401(K), a,
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Osmosis-微生
Osmosis-微生
Osmosis-微生
It's a multidrug resistant bacteria, and it can be treated with cephalosporins, aminoglycosides, fluoroquinolones, and carbapenems in case of beta-lactamase production; only with carbapenems in case of ESBL production; and with colistin, tigecycline or fosfomycin in case of carbapenemases production.
肺炎克雷伯杆菌也是一种多重耐药菌，如果产生β-内酰胺酶，可以用头孢菌素、氨基糖苷
、氟喹诺酮以及碳青
药
；如果产生ESBL，可以只应用碳青进
；如果产生碳青酶，则应用多粘菌素、替加环素或磷素进。
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译
