METHODS Terazosin hydrochloride was synthesized from anhydro-piperazine via acylation,reduction,amination,salification etc.

方法以无水哌嗪为起始原料,经酰、还原、胺、成等反应制酸特拉唑嗪。

The title resin has been prepared by Friedel-Crafts acylation followed by bromination and amination.The method avoids the utilization of cancerogenic chloromethyl methyl ether.

通过付氏酰基反应引入乙酰基，接着溴、胺，标题树脂。该法避免了使用氯甲醚。