The THFA product of hydrogenation in common pressure has been used in enzymatic reaction and expressed the same result as that of THFA from Sigma, the cost of reduction by hydroborates is lower.

常压氢化法的产来代替进口试剂作为酶反应的辅酶，但硼氢化物法成本最低，且能合成满足酶反应要求的产物。