The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.
Chromatin The loose network of threads seen in nondividing nuclei that represents the chromosomal material, consisting of DNA, protein (mainly histone), and small amounts of RNA.
These machines are called chromatin remodelers, and the way they work is that they basically scoot the DNA around these histones and they allow new pieces of DNA to become exposed.
But it also introduces a new problem: your DNA is wrapped SO tightly around the histone that your cell can’t access most of your genetic information anymore.
Your DNA is made up of two strains that wrap around each other in the famous double helix structure, to get even more compact and tiny, that DNA is wrapped around little proteins called histones.