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The transportability through BBB and bioavailability of the inhibitors will be the focus by the systemafic bioassay in vivo.

指出以后的点是进行系统深入的生物体内评价,解决药物透过血脑屏障生物利用度等问题。

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The permeability of blood-brain barrier (BBB) was detected by Evans Blue (EB) leakage method, and the ultrastruncture of BBB, which contained astroglia, was observed under electron microscopy.

伊文思蓝(EB)渗出法检测血脑屏障(BBB)通透性。透观察星形胶质细胞在内的BBB超微结构变化。

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经济学人 Finance and economics

A third of American corporate debt is rated BBB, the lowest investment-grade rating.

三分之一的美国公司债务为 BBB,这最低的投资

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经济学人 Finance and economics

And the ratings that were awarded to the bank—of a3 and bbb respectively—were far from the highest notches available.

该银行获得的(分别为 a3 和 bbb)远低于现​​有的最高

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经济学人-综合

That has been good news for the high-yield, or junk, bond market, where companies with poor credit ratings (below the investment-grade threshold of BBB) turn for finance.

于高收益债券市场或者垃圾债券市场来说,好消息.在那里,低信用的企业,低于投资BBB门槛的企业,可以寻求融资机遇.

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Osmosis-微生物

CSF analysis can also show an elevated protein concentration because the inflammation leads to a more permeable blood brain barrier, or BBB, which is a selective semipermeable barrier between the circulating blood and the central nervous system.

脑脊液检查可有蛋白含量升高,由于炎症导致介于循环血流和中枢神经系统之间的半透膜屏障,即血脑屏障,通透性升高。

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经济学人 Business

At the same time, debt issuance has slowed and yields on American corporate bonds rated bbb, the lowest and most common investment-grade rating, have risen to 5.1%, up from an average of 2.4% in 2021.

与此同时,债务发行放缓,为 bbb 的美国公司债券收益率已从 2021 年的平均 2. 4% 上升至 5. 1%。

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