The transportability through BBB and bioavailability of the inhibitors will be the focus by the systemafic bioassay in vivo.
指出以后的点是进行系统深入的生物体内评价,解决药物透过血脑屏障生物利用度等问题。
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CSF analysis can also show an elevated protein concentration because the inflammation leads to a more permeable blood brain barrier, or BBB, which is a selective semipermeable barrier between the circulating blood and the central nervous system.
脑脊液检查可有蛋白含量升高,由于炎症导致介于循环血流和中枢神经系统之间的半透膜屏障,即血脑屏障,通透性升高。