low-down

Secondly the enzyme is inhibited by an intermediate lower down the metabolic pathway, usually either phosphoenolpyruvate or citrate.

其次，减缓代谢途径一个中间，是磷酸烯醇或柠檬酸降低酶活性。

The directors are clearly responsible for what happened, but they’re sure to find a whipping boy lower down the company.

虽然这事显然是主管责任，但他们肯定会从公司下层里找一个替罪羊。